Module 993: Clinical Neurochemistry & Nutrition II -Energy Production: RBC physiology, Mitochondria and Related Nutrients
By: Carrick Institute for Graduate Studies

The following topics will be covered in Module 2:

• How to Use This Course
• The 4 Neurochemical Priorities (never get lost!)
• The Road map
• How to Work Up a Real Patient
• The 10 Core Principles
• Module 1 Review
  • Myelination and Microbiota
  • Magnesium and Depression
  • Excitotoxicity and Glutamate
  • How to handle a patient with seizures
  • Key points about ALS
  • Functional/Optimal Lab Ranges so far
• Preview of Celiac Disease and Non-Celiac Wheat/Gluten Sensitivity
• Preview of Parkinson’s Disease
• Every Case Study details the patient’s presentation, work up, treatment plan and follow up.
• Case Study – 48 year old woman with fatigue, chronic frequent dry cough
• Blood Tests and Codes for this Module
  • CBC / Differential with Platelet Count
  • Iron
  • IBC
  • Serum Ferritin
  • Serum Methylmalonic Acid
  • Homocysteine
  • Serum Vitamin B12
  • Serum Folic Acid
  • Hereditary Hemochromatosis, DNA Analysis
  • cardiac CRP (or High sensitivity CRP)
  • H. Pylori Urea Breath Test
  • Helicobacter pylori Antibodies, IgA, IgG, IgM
  • Helicobacter pylori Stool Antigen
  • Intrinsic Factor Antibodies
  • Gastric Parietal Cell Antibodies
• Module 2 Tests Functional/Optimal Ranges
• Big Picture of the Neurochemical Priorities
  • #2 – Cellular Energy: RBCs, Nutrients, MItochondria
  • #3 – Cellular Energy: HPA Axis and Glucose Handling
• Lab Reference Ranges vs. Functional/Optimal Ranges
  • What’s the difference?
• Energy Production in the Body
  • Citric Acid Cycle and Nutrient Co-factors
• Physiology of Red Blood Cells
• Understanding Blood Chemistry – For each test:
  • What physiology is actually being tested?
  • What makes it high?
  • What makes it low?
  • What are the lab reference ranges?
  • What is the functional/optimal ranges?
    • RBC
    • Hemoglobin
    • Hematocrit
    • MCV
    • MCH
    • MCHC
    • RDW
    • Platelet count
    • Reticulocyte count
  • CBC Red Blood Cell markers interpretation
    • Anemia Classifications
• Iron Physiology
• Iron Testing
  • What physiology is actually being tested?
  • What makes it high?
  • What makes it low?
  • What are the lab reference ranges?
  • What is the functional/optimal ranges?
    • TIBC
    • UIBC
    • Serum
    • Transferrin Saturation
    • Ferritin
• Iron deficiencies
  • Physical signs and symptoms
  • Iron deficiency and the brain
  • Causes of iron deficiency
• Work up for Iron deficiency and Iron deficiency anemia
• Treatment of Iron Deficiency and Iron deficiency anemia
• Hemochromatosis
• Iron Supplementation
  • How much, what kind and when to take it
• B12 Physiology
  • Absorption
• B12 Testing
  • the problem with the serum B12
  • Methyl Malonic Acid
• Metabolic B12 Deficiency
• Causes of B12 Deficiency
• What causes High levels of B12?
• Signs, Symptoms and Effects of Low B12
• B12 Lab testing interpretation
• B12 Supplementation
  • What kinds, how much and when
• Case Study- 68 year old woman with Parkinson’s
• Case Study – 62 year old woman with depression and dysautonomia
• Folate Physiology
• Testing for Folate status
  • Serum Folate
• Effects of low folate
• Causes of low folate
• Folate supplementation
  • how much, what kind of and when to take it
• Homocysteine and Remethylation
  • Causes of high homocysteine
  • MTHFR
  • Homocysteine and Depression, Bipolar, Schizophrenia, Parkinson’s, Alzheimer’s Disease
  • Testing for homocysteine
  • Treatment of high homocysteine
• Interpreting patterns of RBC markers, Iron, B12, MMA, Folate and Homocysteine
• Effects of Iron Deficiency Anemia
• Case Study – 25 year old woman with hemiparesthesia, blurry vision and dysautonomia
• Case Study – 64 year old man with Parkinson’s
• RBC Patterns on blood chemistry
• Anemias—there’s lots of them
• Treating underlying causes of an anemia
• Case Study – 42 year old woman with fatigue and depression
• Case Study – 29 year old woman with mental sluggishness, fatigue, insomnia
• Case Study – 38 year old woman with anxiety and heart palpitations

• Module 993: Clinical Neurochemistry & Nutrition II -Energy Production: RBC physiology, Mitochondria and Related Nutrients
• By:    Carrick Institute for Graduate Studies
• Instructor:    Dr. David Clark
• Total CE Hours:    25
• Course Format:     Online Distance Learning
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• Course Categories:     Chiropractic Assistants, DC Continuing Education
• Course Subjects | CE HOURS:
  • Neurology  -10 CE Hours
  • Nutrition  -15 CE Hours