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When the gut microbiome is out of balance or inflamed, the impact is felt throughout the body, including the cardiovascular system. If the gut is healthy and functioning properly, microbial metabolites—such as lipopolysaccharide (LPS)—and other antigens are appropriately contained within the gut lumen. However, a dysfunctional, permeable intestinal barrier allows microbial antigens and metabolites to be translocated from the gut into the bloodstream. Once intestinal permeability allows LPS and antigens to escape into circulation, they can trigger immune-response inflammation that contributes to insulin resistance, hypertension, atherosclerosis, coronary artery disease, atrial fibrillation, and cardiomyopathy.
In this incisive new presentation, Dr. Robert Silverman leads you through the intricate interplay between gut microbiota composition, gut permeability, immune-inflammatory responses, metabolic pathways, and their collective influence on cardiovascular well-being. You’ll come away with a thorough understanding of new functional medicine strategies for improved GI system function and how they can help reduce cardiovascular risk and lead to optimal health.
