Course Objective: The objective of this course is to familiarize the DC with dysafferentation as a subluxation theory, comparing and contrasting with other subluxation models. Through exploring receptor function, cervical and vestibular reflexes, nociception and the concepts of maladaptive plasticity in the brain, the DC will gain an insight into how subluxations can affect the nervous system beyond the nerve root. Eight simple tests to assess dysafferentation are presented, as well as an explanation of how adjustments can be used to correct dysafferentation.