Globally the burden of brain disorders continues to The impact vaccines have had on public health cannot be overstated, saving millions of lives every year and preventing disease in millions more. That being said, vaccines are not 100% safe. Some question the importance of mandated vaccination programs for rare diseases, as well as for diseases with high survival rates. Persistent conspiracy theories and gripping anecdotes have spawned anti-vaccination movements in pockets around the world. increase. As populations are growing and aging the prevalence of major disabling brain disorders steeply increase with age.